Therapy, Drugs, and Therapy on Drugs - Attenuated psychotic symptoms,

Journal article

Lukas A. Basedow, Melina F. Wiedmann, Sören Kuitunen-Paul, Veit Roessner, Yulia Golub
European Journal of Psychotraumatology, vol. 14, 2023 Nov, p. 2193327

DOI: 10.1080/20008066.2023.2193327

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APA Click to copy
Basedow, L. A., Wiedmann, M. F., Kuitunen-Paul, S., Roessner, V., & Golub, Y. (2023). Attenuated psychotic symptoms, substance use and self-reported {PTSD} in adolescence. European Journal of Psychotraumatology, 14, 2193327. https://doi.org/10.1080/20008066.2023.2193327

Chicago/Turabian Click to copy
Basedow, Lukas A., Melina F. Wiedmann, Sören Kuitunen-Paul, Veit Roessner, and Yulia Golub. “Attenuated Psychotic Symptoms, Substance Use and Self-Reported {PTSD} in Adolescence.” European Journal of Psychotraumatology 14 (November 2023): 2193327.

MLA Click to copy
Basedow, Lukas A., et al. “Attenuated Psychotic Symptoms, Substance Use and Self-Reported {PTSD} in Adolescence.” European Journal of Psychotraumatology, vol. 14, Nov. 2023, p. 2193327, doi:10.1080/20008066.2023.2193327.

BibTeX Click to copy

@article{basedow2023a,
  title = {Attenuated psychotic symptoms, substance use and self-reported {PTSD} in adolescence},
  year = {2023},
  month = nov,
  journal = {European Journal of Psychotraumatology},
  pages = {2193327},
  volume = {14},
  doi = {10.1080/20008066.2023.2193327},
  author = {Basedow, Lukas A. and Wiedmann, Melina F. and Kuitunen-Paul, Sören and Roessner, Veit and Golub, Yulia},
  month_numeric = {11}
}

ABSTRACT
Background: The occurrence of attenuated psychotic symptoms (APS) is a major concern in populations with substance use disorders (SUDs). However, APS also frequently develop in the course of Post-Traumatic Stress Disorder (PTSD). This study explores how the prevalence of APS differs between adolescent patients with only SUD, SUD with a history of traumatic experiences (TEs), and with SUD and self-reported PTSD.

Methods: We recruited n = 120 treatment-seeking adolescents at a German outpatient clinic for adolescents with SUD. All participants filled out questionnaires assessing APS (PQ-16, YSR schizoid scale), trauma history, PTSD symptoms (both UCLA PTSD Index), and SUD severity (DUDIT) next to an extensive substance use interview. We performed a multivariate analysis of co-variance with the four PQ-16 scales and the YSR scale as outcomes and PTSD status as predictor. Additionally, we performed five linear regressions predicting each PQ-16 score and YSR score based on tobacco, alcohol, cannabis, ecstasy, amphetamine, and methamphetamine use.

Results: Participants with co-occurring SUD and self-reported PTSD showed significantly higher APS prevalence rates (PQ-16 score, p = .00002), more disturbed thought content (p = .000004), more perceptual disturbances (p = .002), more negative symptoms (p = .004) and more thought problems (p = .001) compared to adolescents with SUD and a history of trauma and adolescents with only SUD. Past-year substance use was not predictive for APS prevalence (F(75) = 0.42; p = .86; R2 = .04).

Conclusion: Our data suggests that the occurrence of APS in adolescents with SUD is better explained by co-occurring self-reported PTSD than by substance use frequency or substance class. This finding might indicate that APS might be reduced through treating PTSD or focusing on TEs in SUD therapy.

Attenuated psychotic symptoms, substance use and self-reported PTSD in adolescence

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